Multi-drug Resistant Pseudomonas aeruginosa Isolated from Intensive Care Burn Unit

Multi-drug Resistant Pseudomonas aeruginosa Isolated from Intensive Care Burn Unit

Investigation of MexAB-OprM efflux pump gene expression in clinical isolates of pseudomonas aeruginosa isolated from Intensive Care Unit

Background and Aims: Pseudomonas aeruginosa is one of the most important pathogens of nosocomial infections, especially in the ICU (Intensive Care Unit), which has resistance to a wide range of antibiotics, especially Carbapenems. Among the most important resistance mechanisms of this bacteria against carbapenems are MexAB-OprM efflux pump. Therefore, the aim of this study was to evaluate the g...

Multi-resistant pseudomonas aeruginosa: study of risk factors for its detection at intensive care unit admission

Methods From variables collected prospectively in ENVIN study (national nosocomial infection surveillance study), data was analyzed from 16950 patients admitted in 151 polyvalent ICU during the period from April to June in 2010, as a multipurpose cohort with univariable analysis and a multivariable logistic regression. Multi-resistant Pseudomonas aeruginosa, was defined as being resistant to th...

Imipenem-resistant Pseudomonas aeruginosa strains carry vim-type metallo-beta-lactamases isolated from intensive care unit, Shahid Beheshti Hospital, North of Iran

Background: Pseudomonas aeruginosa is the causing agent of many hospital infections and metallo-beta-lactamases (MBL) are being reported with increasing frequency. The aim of this study was to determine the frequency of metallo-&beta-lactamases (MBL) and VIM-1 gene in multidrug-resistant strains of P. aeruginosa isolates and to compare the methods of phenotypic and molecular detection. Materia...

Drug Susceptibility and Molecular Epidemiology of Pseudomonas aeruginosa Isolated in a Burn Unit

Problem statement: Pseudomonas aeruginosa is an opportunistic pathogen that still develops life-threatening infections in patients with immunological system defects, like burn patients, especially in developing countries. Since this bacterium is naturally resistant to many drugs and is able to get resistance to all effective antibiotics, the infection with this organism is particularly problema...